In 2024, the new government led project aiming to integrate genomic medicine for rare and oncological diseases into German healthcare, is set to change how pathologists work in Germany. Digital and molecular pathology are crucial components of precision medicine, which provide the opportunity to implement advanced technologies, including artificial intelligence-based image analysis and ultra-fast next-generation sequencing. Yet challenges and hurdles remain for such technologies, not least their development and standardisation, and integration into pathology laboratory workflows. The Precision Pathology Forum will address such challenges bringing together pathologists, clinicians, bioinformaticians and developers for problem-solving discussions and fruitful collaborations.